Explore how a true producer cell line can significantly simplify your AAV manufacturing process.
ELEVECTA™ producer cell line
A true producer cell line with all four required genes ― rep, helper, cap, and gene of interest (GOI) ― stably integrated into the host cell’s genome. A single induction step is all that’s needed to initiate AAV production.
Benefits:
- Simplified manufacturing process: Replace multi-step transfection with single-step production by adding an induction reagent.
- Scalability: Scale up seamlessly to achieve large quantities of AAV material.
- Reproducibility: Benefit from a monoclonal cell line from which AAV is produced in an identical manner, enabling consistency from batch to batch.
- Reduced COGS: Skip the need for transfection reagent and any plasmid DNA, which are the most expensive raw materials in classical AAV transient transfection.
Here’s how we work together to elevate your AAV production to the next level
We engineer a stable producer cell line with your capsid and GOI. A research master cell vial is handed over to you to create your good manufacturing practices (GMP) cell bank. Then just expand, scale up, and induce from a single cryovial to start your AAV production.
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Curious about continuous biomanufacturing? Join the Cytiva project team vlog series as we document our proof of concept trial and provide insights to help you efficiently plan and execute your project .
Curious about continuous biomanufacturing? Join the Cytiva project team vlog series as we document our proof of concept trial and provide insights to help you efficiently plan and execute your project .
Curious about continuous biomanufacturing? Join the Cytiva project team vlog series as we document our proof of concept trial and provide insights to help you efficiently plan and execute your project .
Curious about continuous biomanufacturing? Join the Cytiva project team vlog series as we document our proof of concept trial and provide insights to help you efficiently plan and execute your project .
Curious about continuous biomanufacturing? Join the Cytiva project team vlog series as we document our proof of concept trial and provide insights to help you efficiently plan and execute your project .
Curious about continuous biomanufacturing? Join the Cytiva project team vlog series as we document our proof of concept trial and provide insights to help you efficiently plan and execute your project .
Curious about continuous biomanufacturing? Join the Cytiva project team vlog series as we document our proof of concept trial and provide insights to help you efficiently plan and execute your project .
Curious about continuous biomanufacturing? Join the Cytiva project team vlog series as we document our proof of concept trial and provide insights to help you efficiently plan and execute your project .
Curious about continuous biomanufacturing? Join the Cytiva project team vlog series as we document our proof of concept trial and provide insights to help you efficiently plan and execute your project .